When it comes to brain health, development, and neurological function, one vitamin plays a crucial role: folate (vitamin B9). Folate supports DNA production, brain chemistry, and the nervous system. But for some people, folate may not be reaching the brain effectively — even if blood levels appear normal.
This is where the FRAT Test (Folate Receptor Autoantibody Test) from AbsoluteDNA provides important insight.
What Is the FRAT Test?
The FRAT Test is a specialised blood test that detects autoantibodies against the folate receptor alpha (FRα) — the transporter responsible for moving folate from the bloodstream into the brain.
If these autoantibodies are present, they can block or interfere with this transport system. This means folate may not reach the brain efficiently, even when a person is getting enough folate through diet or supplementation.
The FRAT Test helps identify whether this biological barrier exists.
Why Folate Transport to the Brain Matters
Folate is essential for:
Brain development
Neurotransmitter production
Cognitive function
Nervous system regulation
DNA repair and cell growth
When folate is unable to cross into the brain properly, it can affect how the brain functions and develops. This can be especially important in children, adolescents, and individuals experiencing neurological or developmental concerns.
Who Might Benefit From the FRAT Test?
The FRAT Test is often used as part of a broader clinical investigation for individuals experiencing unexplained neurological or developmental symptoms.
It may be relevant for:
Children with developmental delays
Individuals on the autism spectrum
People with learning, memory, or cognitive challenges
Those with neurological or behavioural concerns
Individuals who do not respond as expected to folate supplementation
The test does not diagnose a condition. Instead, it identifies whether folate transport into the brain may be impaired, giving doctors and specialists another valuable data point.
Why Choose AbsoluteDNA for the FRAT Test?
AbsoluteDNA partners with advanced laboratories to provide access to highly specialised diagnostic testing that is not commonly available through standard pathology services.
With AbsoluteDNA, you receive:
Accurate, clinically relevant testing
Clear reporting
Support in understanding your results
A professional, confidential service
We work alongside doctors and specialists to ensure your results can be used to guide appropriate care.
Book Your FRAT Test
If you or your clinician are exploring possible causes of neurological or developmental concerns, the FRAT Test may provide valuable insight into folate transport and brain health.
📞 1300 572 153
📧 info@absolutedna.com.au
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